Drug combination: Atoris 60 & Agen 5
Drug InteractionAtoris 60 & Agen 5
The risk or severity of adverse effects can be increased when Amlodipine is combined with Atorvastatin.
Food interactions and other recommendationsAtoris 60: Avoid alcohol. Avoid drastic changes in dietary habit. Avoid taking grapefruit or grapefruit juice throughout treatment. Grapefruit can significantly increase serum levels of this product. Food may decrease maximum plasma levels and area under the curve, but this is clinically inconsequential according to the manufacturer. Take with low fat meal.
Agen 5: Avoid natural licorice. Grapefruit down regulates post-translational expression of CYP3A4, the major metabolizing enzyme of amlodipine. Grapefruit, in all forms (e.g. whole fruit, juice and rind), can significantly increase serum levels of amlodipine and may cause toxicity. Avoid grapefruit products while on this medication. Take without regard to meals.
Combination of side effects Combination of common side effects of all medicinesAbdominal Pain
Atoris 60 (common)
Agen 5 (common)
Headache
Atoris 60 (very common)
Agen 5 (common)
Nausea
Atoris 60 (uncommon)
Agen 5 (common)
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