Drug combination: Lyrica & Sertivan & Lexaurin 1,5

Compared drugs
Lyrica (pregabalin)
Sertivan (sertraline)
Lexaurin 1,5 (bromazepam)
Drug Interaction
Lyrica & Sertivan
The risk or severity of adverse effects can be increased when Pregabalin is combined with Sertraline.

Lyrica & Lexaurin 1,5
The therapeutic efficacy of Bromazepam can be increased when used in combination with Pregabalin.

Sertivan & Lexaurin 1,5
The metabolism of Bromazepam can be decreased when combined with Sertraline.

Food interactions and other recommendations

Lyrica: Avoid alcohol (may increase CNS effects). When taken with food, Cmax decreases, while Tmax is prolonged. Despite these observations, the total absorption of pregabalin is not effected to a clinically relevant degree. Pregabalin can be taken with or without food.
Sertivan: Avoid alcohol. Avoid St.John's Wort. Avoid taking with grapefruit juice. Take with food.
 
Combination of side effects
Combination of common side effects of all medicines
ataxia
Lyrica (uncommon)
Sertivan (uncommon)
Lexaurin 1,5 (very common)

Confusion
Lyrica (uncommon)
Sertivan (common)
Lexaurin 1,5 (uncommon)

Dizziness
Lyrica (very common)
Sertivan (uncommon)
Lexaurin 1,5 (common)

Headache
Lyrica (very common)
Sertivan (uncommon)
Lexaurin 1,5 (uncommon)

Nausea
Lyrica (very common)
Sertivan (uncommon)
Lexaurin 1,5 (uncommon)

Vomiting
Lyrica (common)
Sertivan (common)
Lexaurin 1,5 (uncommon)


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